Here are some general tips to keep your Mac's hard drive trim and slim as possible

You should never, EVER let a conputer hard drive get completely full, EVER!
With Macs and OS X, you shouldn't let the hard drive get below 15 GBs or less of free data space.
Note: If your drive is an SSD, you won’t be able to click “Security Options” as this option will be grayed out. It’s because SSDs don’t have to go through this process due to the way it manages files. Wipe External Hard Drive on Mac via Terminal (Command Line) If for any reason Disk Utility fails to wipe your drive.
- Today, we're showing you how to clean your Apple Computer to make it run faster and free up disk space. If your Mac is running slow, this video is for YOU!
- The newer APFS is best for solid-state drives, and Mac OS Extended (Journaled) is best for older, mechanical hard drives. Scheme: Choose GUID Partition Map. Next, click Erase and after Disk Utility.
Clean Hard Drive For Mac
If it does, it's time for some hard drive housecleaning.
Follow some of my tips for cleaning out, deleting and archiving data from your Mac's internal hard drive.
Have you emptied your Mac's Trash icon in the Dock?
If you use iPhoto or Aperture, both have its own trash that needs to be emptied, also.
If you store images in other locations other than iPhoto, then you will have to weed through these to determine what to archive and what to delete.
If you are an iMovie user, iMovie has its own individual Trash location that needs to be emptied, too!
If you use Apple Mail app, Apple Mail also has its own trash area that needs to be emptied, too!
Delete any old or no longer needed emails and/or archive to disc, flash drives or external hard drive, older emails you want to save.
Look through your other Mailboxes and other Mail categories to see If there is other mail you can archive and/or delete.
STAY AWAY FROM DELETING ANY FILES FROM OS X SYSTEM FOLDER!
Look through your Documents folder and delete any type of old useless type files like 'Read Me' type files.
Again, archive to disc, flash drives, ext. hard drives or delete any old documents you no longer use or immediately need.
Look in your Applications folder, if you have applications you haven't used in a long time, if the app doesn't have a dedicated uninstaller, then you can simply drag it into the OS X Trash icon. IF the application has an uninstaller app, then use it to completely delete the app from your Mac.
To find other large files, download an app called Omni Disk Sweeper.
Download an app called OnyX for your version of OS X.
When you install and launch it, let it do its initial automatic tests, then go to the cleaning and maintenance tabs and run the maintenance tabs that let OnyX clean out all web browser cache files, web browser histories, system cache files, delete old error log files.
Typically, iTunes and iPhoto libraries are the biggest users of HD space.
move these files/data off of your internal drive to the external hard drive and deleted off of the internal hard drive.
If you have any other large folders of personal data or projects, these should be archived or moved, also, to the optical discs, flash drives or external hard drive and then either archived to disc and/or deleted off your internal hard drive.
Moving iTunes library
Moving iPhoto library

Moving iMovie projects folder
Good Luck!
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